Scintiscans and carcinoid tumors.
Identifieur interne : 004896 ( Main/Exploration ); précédent : 004895; suivant : 004897Scintiscans and carcinoid tumors.
Auteurs : RBID : pubmed:7985096English descriptors
- KwdEn :
- 3-Iodobenzylguanidine, Adolescent, Adult, Aged, Aged, 80 and over, Carcinoid Tumor (radionuclide imaging), Child, Female, Humans, Indium Radioisotopes (diagnostic use), Iodine Radioisotopes (diagnostic use), Iodobenzenes (diagnostic use), Male, Middle Aged, Octreotide (diagnostic use), Prospective Studies, Somatostatin (analogs & derivatives), Somatostatin (diagnostic use).
- MESH :
- chemical , analogs & derivatives : Somatostatin.
- chemical , diagnostic use : Indium Radioisotopes, Iodine Radioisotopes, Iodobenzenes, Octreotide, Somatostatin.
- chemical : 3-Iodobenzylguanidine.
- radionuclide imaging : Carcinoid Tumor.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Female, Humans, Male, Middle Aged, Prospective Studies.
Abstract
The presence of somatostatin receptors on carcinoid tumors mediates imaging of tumor extent and inhibition of tumor growth and marker secretion. This prospective study aimed to evaluate radiolabeled somatostatin analog scans in the therapeutic workup of carcinoids.
PubMed: 7985096
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Scintiscans and carcinoid tumors.</title>
<author><name sortKey="Carnaille, B" uniqKey="Carnaille B">B Carnaille</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of General and Endocrine Surgery, University Hospital, Lille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of General and Endocrine Surgery, University Hospital, Lille</wicri:regionArea>
<placeName><region type="région">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nocaudie, M" uniqKey="Nocaudie M">M Nocaudie</name>
</author>
<author><name sortKey="Pattou, F" uniqKey="Pattou F">F Pattou</name>
</author>
<author><name sortKey="Huglo, D" uniqKey="Huglo D">D Huglo</name>
</author>
<author><name sortKey="Deveaux, M" uniqKey="Deveaux M">M Deveaux</name>
</author>
<author><name sortKey="Marchandise, X" uniqKey="Marchandise X">X Marchandise</name>
</author>
<author><name sortKey="Proye, C" uniqKey="Proye C">C Proye</name>
</author>
</titleStmt>
<publicationStmt><date when="1994">1994</date>
<idno type="RBID">pubmed:7985096</idno>
<idno type="pmid">7985096</idno>
<idno type="wicri:Area/Main/Corpus">004B09</idno>
<idno type="wicri:Area/Main/Curation">004B09</idno>
<idno type="wicri:Area/Main/Exploration">004896</idno>
</publicationStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>3-Iodobenzylguanidine</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Carcinoid Tumor (radionuclide imaging)</term>
<term>Child</term>
<term>Female</term>
<term>Humans</term>
<term>Indium Radioisotopes (diagnostic use)</term>
<term>Iodine Radioisotopes (diagnostic use)</term>
<term>Iodobenzenes (diagnostic use)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Octreotide (diagnostic use)</term>
<term>Prospective Studies</term>
<term>Somatostatin (analogs & derivatives)</term>
<term>Somatostatin (diagnostic use)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Somatostatin</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Indium Radioisotopes</term>
<term>Iodine Radioisotopes</term>
<term>Iodobenzenes</term>
<term>Octreotide</term>
<term>Somatostatin</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>3-Iodobenzylguanidine</term>
</keywords>
<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Carcinoid Tumor</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Child</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
</keywords>
</textClass>
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</teiHeader>
<front><div type="abstract" xml:lang="en">The presence of somatostatin receptors on carcinoid tumors mediates imaging of tumor extent and inhibition of tumor growth and marker secretion. This prospective study aimed to evaluate radiolabeled somatostatin analog scans in the therapeutic workup of carcinoids.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">7985096</PMID>
<DateCreated><Year>1995</Year>
<Month>01</Month>
<Day>05</Day>
</DateCreated>
<DateCompleted><Year>1995</Year>
<Month>01</Month>
<Day>05</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0039-6060</ISSN>
<JournalIssue CitedMedium="Print"><Volume>116</Volume>
<Issue>6</Issue>
<PubDate><Year>1994</Year>
<Month>Dec</Month>
</PubDate>
</JournalIssue>
<Title>Surgery</Title>
<ISOAbbreviation>Surgery</ISOAbbreviation>
</Journal>
<ArticleTitle>Scintiscans and carcinoid tumors.</ArticleTitle>
<Pagination><MedlinePgn>1118-21; discussion 1121-2</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The presence of somatostatin receptors on carcinoid tumors mediates imaging of tumor extent and inhibition of tumor growth and marker secretion. This prospective study aimed to evaluate radiolabeled somatostatin analog scans in the therapeutic workup of carcinoids.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Twenty-one patients with carcinoids underwent 26 scans with iodine octreotide or indium pentetreotide. The results for tumor and metastases imaging were analyzed and compared with those of a short inhibition test of marker secretion and with those of metaiodobenzylguanidine scan.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The sensitivity for obtaining images of the overall 43 tumor sites was 72%. We had no false-positive results. Unknown tumor sites were discovered in three patients. The results were slightly better with indium pentetreotide and metastases imaging. A positive scan did not always preclude responsiveness to the functional effect of octreotide. Results of somatostatin analog scans were better than those with metaidobenzylguanidine. The two techniques were complementary in one patient.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The choice of treatment for patients with carcinoid tumors should benefit from functional inhibition test with octreotide and from indium pentetreotide and metaidobenzylguanidine scans.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Carnaille</LastName>
<ForeName>B</ForeName>
<Initials>B</Initials>
<Affiliation>Department of General and Endocrine Surgery, University Hospital, Lille, France.</Affiliation>
</Author>
<Author ValidYN="Y"><LastName>Nocaudie</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Pattou</LastName>
<ForeName>F</ForeName>
<Initials>F</Initials>
</Author>
<Author ValidYN="Y"><LastName>Huglo</LastName>
<ForeName>D</ForeName>
<Initials>D</Initials>
</Author>
<Author ValidYN="Y"><LastName>Deveaux</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Marchandise</LastName>
<ForeName>X</ForeName>
<Initials>X</Initials>
</Author>
<Author ValidYN="Y"><LastName>Proye</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType>Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>UNITED STATES</Country>
<MedlineTA>Surgery</MedlineTA>
<NlmUniqueID>0417347</NlmUniqueID>
<ISSNLinking>0039-6060</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance>Indium Radioisotopes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance>Iodine Radioisotopes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance>Iodobenzenes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>138661-02-6</RegistryNumber>
<NameOfSubstance>pentetreotide</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>35MRW7B4AD</RegistryNumber>
<NameOfSubstance>3-Iodobenzylguanidine</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>51110-01-1</RegistryNumber>
<NameOfSubstance>Somatostatin</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>RWM8CCW8GP</RegistryNumber>
<NameOfSubstance>Octreotide</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N">3-Iodobenzylguanidine</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Aged, 80 and over</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Carcinoid Tumor</DescriptorName>
<QualifierName MajorTopicYN="Y">radionuclide imaging</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Indium Radioisotopes</DescriptorName>
<QualifierName MajorTopicYN="Y">diagnostic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Iodine Radioisotopes</DescriptorName>
<QualifierName MajorTopicYN="Y">diagnostic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Iodobenzenes</DescriptorName>
<QualifierName MajorTopicYN="N">diagnostic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Octreotide</DescriptorName>
<QualifierName MajorTopicYN="Y">diagnostic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Somatostatin</DescriptorName>
<QualifierName MajorTopicYN="Y">analogs & derivatives</QualifierName>
<QualifierName MajorTopicYN="N">diagnostic use</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1994</Year>
<Month>12</Month>
<Day>1</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>1994</Year>
<Month>12</Month>
<Day>1</Day>
<Hour>0</Hour>
<Minute>1</Minute>
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<PubMedPubDate PubStatus="entrez"><Year>1994</Year>
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<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">7985096</ArticleId>
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</record>
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